In Pennsylvania, one engineer is maneuvering a train in the yard and accidentally leaves the train operating without the pneumatic brakes engaged. The operation department initially believes it is a coaster but soon the operators realize that the unmanned train is running on full power. Further, it is carrying dangerous chemicals and diesel in the cargo wagons. There are many unsuccessful attempts to stop the runaway train and the veteran engineer Frank Barnes and the young conductor Will Colson decide to take the chance to reduce the speed of the train with the most unlikely operation.