"Disappeared" is a police drama that tells the story of Sonia Ledesma, a police inspector who joins Group 2 of the Central Brigade, directed by veteran Chief Inspector Santiago Abad. Affected herself by the drama of the disappearance of a close person, she will find in her colleagues Rodrigo, Sebas, and Azhar a new family. Altogether, as a team and with the claim: "we keep looking", they try to solve the most disparate cases, and all of them starring people who were one day swallowed by the earth. To achieve this, they have the collaboration of Help Disappeared, an NGO directed by Carmen Fuentes. The relationship between Carmen and Group 2 goes beyond professional since Santiago was in charge of investigating the disappearance of her son years ago.